Against Claudio Ranieri’s side, Rooney, who has scored just two league goals in 12 appearances this season, was again anonymous before he was substituted with 68 minutes played.
However, Van Gaal said his decision to replace the United captain was a tactical one, rather than being motivated by an injury, as neither Rooney nor Anthony Martial were looking to threaten Leicester’s back four.
“No, I don’t think it’s an injury to Wayne. I wanted to change one of the strikers,'” Van Gaal said.
“It could have been Martial or it could have been Rooney because they were not always running behind the central defenders, and I want that.
“Because of this, I wanted to change but then he was limping and then the choice was easy for me to make.”